Season 10 saw a significant shake-up at the table, with original panellists Star Jones and Meredith Vieira leaving, and comedian and actress Rosie O'Donnell joining.
Danica Patrick, Diane Lane, Outkast 01
9/4/2006
Adrien Brody, Joely Fisher 02
9/6/2006
Maggie Gyllenhaal, Abigail Breslin 03
9/7/2006
Julianne Moore, David Duchovny 04
9/8/2006
Damon Wayans, Jeff Probst 06
9/12/2006
Kevin Costner, Ashton Kutcher 09
9/15/2006
Dr. Phil McGraw, Robin McGraw, Lionel Richie 10
9/18/2006
Jaime Pressly, Ty Pennington, Julio Iglesias 11
9/19/2006
Ben Affleck, Fergie, James McGreevey 12
9/20/2006
Jennifer Love Hewitt, Clay Aiken, Jeremy Iversen 14
9/22/2006
Martin Short, Donny Osmond, Arianna Huffington 15
9/25/2006
Ray Liotta, Bridget Moynahan 16
9/26/2006
Victor Garber, Carnie Wilson, Tina Yothers, Natalie Cole 17
9/27/2006
Jamie Lee Curtis, Salma Hayek, America Ferrera, Bob Seger 18
9/28/2006
Patrick Dempsey, Dr. Michelle Bachelet 19
9/29/2006
Cynthia Nixon, Julian McMahon, Dylan Walsh 20
10/2/2006
Dennis Haysbert, Tyler Florence 21
10/3/2006
Morgan Freeman, Scott Wolf 22
10/4/2006
Whoopi Goldberg, Andy Dick, "Project Runway" finalists 24
10/6/2006
John Lithgow, Suzanne Somers, Amy Grant 26
10/10/2006
Gloria Estefan, Lynn Sherr 27
10/11/2006
Nick Lachey, Helen Mirren, Arianna Huffington 28
10/12/2006
Alec Baldwin, Indigo Girls 29
10/13/2006
Sigourney Weaver, Dylan Walsh, Julian McMahon, Ruben Studdard 30
10/16/2006
Martha Stewart, Donal Logue 31
10/17/2006
Bill O'Reilly, Kate Walsh, Trinny and Susannah 32
10/18/2006
Tom Bergeron, Elizabeth Edwards, Cheetah Girls 33
10/19/2006
Kirsten Dunst, Jason Schwartzman, Caroline Rhea 34
10/20/2006
Vanessa Williams, Isaac Mizrahi, Sarah Chalke, Geralyn Lucas, guest co-host Judge Glenda Hatchett 35
10/23/2006
Tim Robbins, Elizabeth Perkins, Lonestar 36
10/24/2006
Jane Fonda, Ellen Burstyn 37
10/25/2006
Ricardo Chavira, Phil Rosenthal, John Legend, guest co-host Tara Reid 38
10/26/2006
Nathan Lane, Amy Berg, guest co-host Sade Baderinwa 39
10/27/2006
Hugh Jackman, Kate Winslet, Christine Ebersole 40
10/30/2006
Courtney Love, Penn & Teller, guest co-host Kathie Lee Gifford 41
10/31/2006
Charles Gibson, Joan Collins 42
11/1/2006
Gary Sinise, Kellie Pickler, guest co-host Arthel Neville 43
11/2/2006
Tim Allen, Martin Short, Barry Manilow, guest co-host Arthel Neville 44
11/3/2006
Ed Harris, Skeet Ulrich, Cameron Mathison 45
11/6/2006
Alec Baldwin, Mario Cantone 47
11/8/2006
Kyle MacLachlan; Harry Shearer, Catherine O'Hara, Parker Posey 49
11/10/2006
Guest co-host Jacque Reid, Cindy Crawford, Josh Radnor, Cobie Smulders 50
11/13/2006
Guest co-host Monique Coleman, Anthony Geary, Genie Francis, Chester Gregory II 51
11/14/2006
Jeff Foxworthy, Mike Rowe 53
11/16/2006
Helen Hunt, Milo Ventimiglia, Masi Oka 55
11/20/2006
Guest co-host Sherri Shepherd, James Spader, Jim Gaffigan 56
11/21/2006
Guest co-host Sherri Shepherd, Hugh Jackman, Rachel Weisz, Robert Verdi 58
11/24/2006
Guest Co-Host Amy Holmes, Matthew Broderick, Marlo Thomas, Andrea Bocelli 59
11/27/2006
Guest Co-Host Victoria Rowell 60
11/28/2006
Thomas Gibson, Danny DeVito 61
11/29/2006
Josh Duhamel, Iman, guest co-host Renee Goldsberry 63
12/1/2006
Marla Sokoloff, Kyra Sedgwick, guest co-host Samantha Harris 64
12/4/2006
Jenny McCarthy, Julia Sweeney, the Von Trapps, guest co-host Shaun Robinson 65
12/5/2006
James Brolin, Jeffrey Carlson 66
12/6/2006
Wilmer Valderrama, cast of Broadway's "Mary Poppins" 67
12/7/2006
Dakota Fanning, Mitch Albom, guest co-host Shaun Robinson 68
12/8/2006
Fantasia, Susan Sarandon, guest co-host Dari Alexander 72
12/14/2006
Gladys Knight, Julianne Moore, guest co-host Dari Alexander 73
12/15/2006
Bryan Fogel, Martha Stewart, Sam Wolfson, guest co-host Sherri Shepherd 74
12/18/2006
Kristin Chenoweth, Judy Gold, Edward Norton, guest co-host Jacque Reid 75
12/19/2006
Sen. Hillary Rodham Clinton, Kaye Ballard, guest co-host Crystal McCrary Anthony 76
12/20/2006
Ewan McGregor, the Children's Christmas Choir 77
12/21/2006
Matthew McConaughey, Matthew Fox, Anthony Mackie, Kate Mara, a performance by the Broadway cast of "Rent" 78
12/22/2006
Cate Blanchett, Carla Gugino, guest co-host Sherri Shepherd 79
12/27/2006
LL Cool J, guest co-host Sherri Shepherd 80
1/2/2007
Erin Gruwell, April L. Hernandez, Donal Logue, Hilary Swank, guest co-host Sherri Shepherd 81
1/3/2007
Lucy Liu, Michael Urie, guest co-host Sherri Shepherd 82
1/4/2007
Nicollette Sheridan, Robert Verdi, guest co-host Sherri Shepherd 83
1/5/2007
Kaley Cuoco, Jennifer Hudson 84
1/8/2007
David Arquette, guest co-host Lola Oguinnaike 85
1/9/2007
Sarah Ferguson, Sam Harris 86
1/10/2007
Cybill Shepherd, guest co-host Kerry Washington 87
1/11/2007
Jo Frost, Patricia Heaton 89
1/15/2007
Mario Cantone, LL Cool J, Nancy Wilson 90
1/16/2007
Rupert Everett, The Wiggles, guest co-host April Lee Hernandez 91
1/17/2007
Juliette Binoche, Raquel Welch, gest co-host Kellie Pickler 92
1/18/2007
Kathy Griffin, Les Stroud, guest co-host Kellie Pickler 93
1/19/2007
Lizzy Caplan, Heather Goldenhersh, Justin Chambers 94
1/22/2007
Marc Summers, Forest Whitaker 96
1/24/2007
Tony Danza, Lou Dobbs, guest co-host Tina Fey 97
1/25/2007
Duff Goldman, Jeremy Piven 98
1/26/2007
Guest co-host Toni Braxton 99
1/29/2007
Harry Connick Jr., Kristin Davis, guest co-host Whoopi Goldberg 100
1/30/2007
Mary Hart, guest co-host Jane Krakowski 101
1/31/2007
Sarah Silverman, Marcel Vigneron, Goran Visnjic 102
2/1/2007
Kevin Bacon, Chelsea Handler, Joy Mangano, guest co-host Whoopi Goldberg 103
2/2/2007
Regis Philbin, Sendhil Ramamurthy 104
2/5/2007
Yunjin Kim, Jackie Earle Haley 105
2/6/2007
Miley Cyrus, Emily Deschanel 106
2/7/2007
Hilary Duff, John Tartaglia, guest co-host Kristin Chenoweth 107
2/8/2007
Josh Groban, guest co-host Kristin Chenoweth 108
2/9/2007
Mario Cantone, Eva Longoria 109
2/12/2007
Anita Baker, Dave Koz, John Stamos, guest co-host Jo Frost 110
2/13/2007
Adrian Pasdar, Eric Mabius 112
2/15/2007
Jack Coleman, guest co-host Sherri Shepherd 114
2/19/2007
Richard Lewis, David Tutera, guest co-host Sherri Shepherd 115
2/20/2007
Jim Carrey, a performance from the Broadway musical "Spring Awakening" by Remy Zaken 117
2/22/2007
Samuel L. Jackson, Christina Ricci, guest co-host Sherri Shepherd 118
2/23/2007
Tom Bergeron, Angela Lansbury 119
2/26/2007
Cheutine Fong, Jane Seymour, Von Smith, guest co-host Kimberly McCullough 120
2/27/2007
Angela Bassett, Courtney B. Vance 121
2/28/2007
Dennis Miller, Suze Orman 122
3/1/2007
Evangeline Lilly, guest co-host S. Epatha Merkerson 123
3/2/2007
Rachael Ray, Bob and Lee Woodruff 124
3/5/2007
Ken Davitian, Skeet Ulrich, guest co-host Constance Marie 125
3/6/2007
Phyllis Diller, Kelsey Fowler 126
3/7/2007
Queen Latifah, Mark Indelicato, guest co-host Kimberley Locke 127
3/8/2007
Laura Prepon, Richard Jeni, Minnie Driver, Senator Charles Schumer, guest co-host Jacque Reid 129
3/12/2007
Roseanne, guest co-host Joely Fisher 130
3/13/2007
Delta Burke, guest co-host Susie Essman 131
3/14/2007
Julian McMahon, Rich Little 132
3/15/2007
Chris Rock, Kerry Washington, Cyndi Lauper 133
3/16/2007
Rory Kennedy, Rick Schroder, Nelly Furtado and Timbaland 134
3/19/2007
Bea Arthur, Adrienne Barbeau, guest co-host Audra McDonald 135
3/20/2007
The cast of "A Chorus Line", the cast of "Les Miserables", LaChanze, Elisabeth Withers-Mendes, baker Marjorie Johnson 136
3/21/2007
Don Cheadle, William S. Cohen, Janet Langhart Cohen 137
3/22/2007
Tim McGraw, guest co-host Joely Fisher 138
3/23/2007
John Lithgow, guest co-host Beth Ostrosky 140
3/27/2007
Patricia Arquette, Macy Gray, guest co-host Jacque Reid 141
3/28/2007
Jonathan Rhys Meyers, guest co-host Marcia Gay Harden 142
3/29/2007
Camryn Manheim, Andy Baldwin 143
3/30/2007
Jerry Stiller, guest co-host Valerie Bertinelli 144
4/9/2007
David Hyde Pierce, Martina McBride 145
4/10/2007
Lorraine Bracco, Victoria Rowell, guest co-host Jamie-Lynn Sigler 146
4/11/2007
Molly Shannon, Leeza Gibbons, guest co-host Rose McGowan 147
4/12/2007
Robert Wagner, Robert Vaughn, "The Pirate Queen" cast, guest co-host Rene Syler 150
4/17/2007
Craig Ferguson, Rue McClanahan, guest co-host Aisha Tyler 151
4/18/2007
Jessica Biel, Clyde Drexler, Olympia Dukakis, Elena Grinenko 152
4/19/2007
Sigourney Weaver, guest co-host Whoopi Goldberg 153
4/20/2007
Vanessa Redgrave, guest co-host Regina King 155
4/24/2007
Tyra Banks, Heather Mills, Jonathan Roberts, guest co-host Carrie Ann Inaba 157
4/26/2007
Judy Gold, Miranda Lambert, Natalie Portman, guest co-host Ricki Lake 160
5/1/2007
Marcia Cross, Eric Mabius, John Ratzenberger, Edyta Sliwinska, guest co-host Jenny McCarthy 162
5/3/2007
Edie Falco, Peter Krause, Natalie Portman, guest co-host Judy Gold 163
5/4/2007
James Denton, Nora Ephron, guest co-host Alison Stewart 164
5/7/2007
Hayden Panettiere, Robin Thicke, guest co-host Sarah Ferguson 165
5/8/2007
Gena Rowlands, Brooke Shields, guest co-host Goldie Hawn 166
5/9/2007
Geoffrey Rush, James Pickens Jr., Billy Ray Cyrus, guest co-host Marie Osmond 167
5/10/2007
Felicity Huffman, Dean Obeidallah 168
5/11/2007
Tyne Daly, Sharon Gless, Ali Larter, guest co-host Lee Woodruff 169
5/14/2007
David Boreanaz, William Shatner 170
5/15/2007
Dave Annable, Balthazar Getty, Kathy Griffin, Avril Lavigne, Sara Ramirez 171
5/16/2007
Cheryl Burke, Josh Holloway, Ian Ziering, guest co-host Chandra Wilson 172
5/17/2007
Andy Baldwin, Doug Savant 174
5/21/2007
Andy Baldwin, Tessa Horst, Dominic Monaghan, guest co-host Kassie DePaiva 175
5/22/2007
Laila Ali, Joey Fatone, Elizabeth Mitchell, Alicia Silverstone, guest co-host Sherri Shepherd 176
5/23/2007
Apolo Anton Ohno, Kathy Griffin, Korey Rowe, Dylan Avery, William Rodriguez, guest co-host Sherri Shepherd 177
5/24/2007
Jeanne Bice, The Clever Cleaver Brothers, B. Smith, David Tutera, guest co-host Padma Lakshmi 178
5/25/2007
Jimmy Fallon, Audra McDonald, Jeffrey Ross 180
5/29/2007
Sara Blakely, Cathleen Black, Meg Whitman, guest co-host Suze Orman 181
5/30/2007
Debra Messing, Judy Davis, Anika Noni Rose, a performance by the Broadway cast of "Legally Blonde" 182
5/31/2007
Jane Seymour, guest co-host Lori Stokes 183
6/1/2007
Wayne Brady, Ne-Yo, guest co-host Kathy Griffin 184
6/4/2007
Ross Mathews, Martha Stewart, guest co-host Kathy Griffin 185
6/5/2007
Liev Schreiber, Lynne Spears, guest co-host Sherri Shepherd 186
6/6/2007
Mario Cantone, Marg Helgenberger, guest co-host Lorraine Bracco 187
6/7/2007
Robert Iler, Burt Pugach, Linda Pugach, guest co-host Kathy Griffin 188
6/8/2007
Seth Green, Rihanna, guest co-host Kim Coles 189
6/11/2007
The Puppini Sisters, Judge Judy Sheindlin, guest co-host Rene Syler 190
6/12/2007
Anthony Michael Hall, Denis Leary, guest co-host Jacque Reid 191
6/13/2007
Blake Lewis, Michael Smerconish, Jordin Sparks, guest co-host Kim Coles 192
6/14/2007
Jessica Alba, Grace Anne Koppel, Ted Koppel, cast members from "One Life to Live", guest co-host Sherri Shepherd 193
6/15/2007
Mario Cantone, Kyra Sedgwick, guest co-host Margaret Cho 194
6/18/2007
Toby Keith, Michael Moore, guest co-host Star Parker 195
6/19/2007
Bon Jovi, guest co-host Gayle King 196
6/20/2007
Fran Drescher, Lucy Liu, guest co-hosts Gayle King, Sherri Shepherd 197
6/21/2007
Steve Carell, Steven Lamm, Wanda Sykes, guest co-host Molly Shannon 198
6/22/2007
Jackie Collins, Tina Brown, guest co-hosts Whoopi Goldberg, Sherri Shepherd 199
7/9/2007
Jaclyn Smith, John Ratzenberger, guest co-host Alexandra Wentworth 200
7/10/2007
Kelly Rowland, Jason Thompson, Billy Dee Williams, Mary Tyler Moore, guest co-host Debi Mazar 201
7/11/2007
Joan Rivers, chef Ingrid Hoffman, guest co-host Mario Cantone 202
7/12/2007
Tom Bergeron, Perez Hilton, guest co-hosts Whoopi Goldberg, Sherri Shepherd 203
7/13/2007
Harry Hamlin, Lisa Rinna, guest co-host Sherri Shepherd 204
7/16/2007
Kristin Chenoweth, guest co-host Ross Mathews 205
7/17/2007
Alan Alda, Taylor Hicks, guest co-host Sherri Shepherd 206
7/18/2007
Glenn Close, bubble performer Fan Yang, guest co-host Paula Abdul 207
7/19/2007
Ashley Judd, guest co-host Sherri Shepherd 208
7/20/2007
Amanda Bynes, guest co-host Victoria Recano 209
7/23/2007
Minnie Driver, guest co-host Maria Menounos 210
7/24/2007
Cheryl Ladd, James Marsden, guest co-host Giuliana DePandi 211
7/25/2007
Martin Sheen, Billy Ray Cyrus, guest co-host Dayna Devon 212
7/26/2007
Queen Latifah, John Travolta, guest co-host Sherri Shepherd 213
7/27/2007
Jason Priestley, Sugarland, guest co-host Nancy Grace 214
7/30/2007
George Lopez, Alan Jackson and his wife Denise, guest co-host Joan Rivers 215
7/31/2007
Julia Stiles, Zac Efron, guest co-host Chelsea Handler 217
8/2/2007
Anderson Cooper, Nina Garcia, guest co-hosts Caroline Rhea and Melissa Claire Egan 218
8/3/2007
Ashley Tisdale, Drake Bell, Josh Peck, Alyson and Amanda Michalka, children from "Are You Smarter Than a 5th Grader?", guest co-host Maria Lark 219
9/3/2007
