Williams is the author of four novels. Her first, State of Grace (1973), was nominated for a National Book Award for Fiction. Her most recent novel, The Quick and the Dead (2000), was a finalist for the Pulitzer Prize for Fiction. Her first collection of short stories was Taking Care, published in 1982. A second collection, Escapes, followed in 1990. A 2001 essay collection, Ill Nature: Rants and Reflections on Humanity and Other Animals, was a finalist for the National Book Critics Circle Award for Criticism. Honored Guest, a collection of short stories, was published in 2004. A 30th anniversary reprint of The Changeling was issued in 2008 with an introduction by the American novelist Rick Moody.

Her stories and essays are frequently anthol